Substitution at R3 with a halogen or alkoxy group (74f–74i) led to a slight boost in cellular potency With all the halide analogs (74g–h) showing highest the potency from the group. Further more optimization brought about the discovery of 74i–j, with 74k as quite possibly the most Energetic compound while https://juliusqnhwk.ampblogs.com/a-secret-weapon-for-indazole-carboxamide-68232124