Epidural clonidine applied as an adjunct to community anesthetics has three distinct mechanisms of action. First, the stimulation of alpha-two-receptors from the dorsal horn reduces soreness transmission. Next, clonidine could potentially cause community vasoconstriction that boundaries vascular removal of local epidural anesthetics. Jun 10, 2024 · If clonidine therapy https://www.proleviate.com/post/the-new-pain-killer-conolidine