Epidural clonidine applied as an adjunct to local anesthetics has a few distinct mechanisms of action. Initial, the stimulation of alpha-2-receptors from the dorsal horn lessens suffering transmission. Secondly, clonidine can cause local vasoconstriction that restrictions vascular elimination of area epidural anesthetics. Clonidine is distributed in breast milk; warning https://tbookmark.com/story19680170/5-easy-facts-about-onolidine-described