Pentobarbital will decrease the level or effect of ketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of levoketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. When barbiturates like Nembutal are abused, they are not usually the primary drug o... https://exactlybookmarks.com/story20250965/un-imparziale-vista-pentobarbital-hond