Research into conolidine has led to discovery of the opioid receptor in the human body named ACKR3/CXCR7. ACKR3 seems to be quite possibly the most desired focus on for conolidine, which also disregards the other four classical opioid receptors(3). Conolidine has long been present in the tabernaemontana divaricata plant, https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers